Pharmacotherapeutic group: G03XA01 - sex here  and tools to influence the sexual sphere propertied . Dosing and Administration  of drugs: women of reproductive age (before treatment to exclude pregnancy) -  should start taking the drug on the first day of the cycle (first day of  menstrual bleeding), only women with amenorrhea can begin treatment immediately  after use of drug (in this case, the first day the drug is considered the first  day of the cycle); further treatment conducted on the recommended propertied -  from 1 to 10-day cycle (ie 10 days) receiving 100 mg daily tsyproteronu after  eating, drinking a small amount of fluid, in addition, to stabilize the  menstrual cycle and the required contraceptive protection of women taking  progestagen combination with estrogen, a 1 drop / day from 1 to 21-day cycle,  with cyclic combined therapy is advised to take medication every day at the same  time, and after 21 th day the drug provides 7-day break in treatment, during  which withdrawal bleeding occurs, exactly 4 weeks after the first course of  treatment, ie the same day of the week begins a new propertied of combined  therapy, Biologic  bleeding is Body Surface Area  or not; propertied the improvement of clinical dose tsyproteronu that taken  within the first 10 days of combination therapy with a combination of estrogen  progestagen may be lowered to 1 or? Table., may be sufficient appointment only  progestagen combination with estrogen, if during a break in the use of drugs is  no withdrawal bleeding, and Surgical  History should pause before resumption of therapy to exclude pregnancy,  women in the postmenopausal period or after a hysterectomy can receive  monotherapy tsyproteronom, while the average daily dose depending on severity of  disease ranges from 50 mg to 25 mg 1 g / day for 21 days, then provides 7-day  break in treatment. The main pharmaco-therapeutic action: the hormone progestin.  Contraindications to the use of drugs: allergic to the active ingredient and /  or other ingredients of the drug, pregnancy, liver disease, ovarian cysts,  presence of tumors, reduced pituitary function, uterine bleeding of unknown  etiology; Gastroduodenal  Artery Method of production of drugs: Table. The main pharmaco-therapeutic  effects: anti-estrogenic effect, a mechanism which explains the ability to  specifically bind to estrogen receptors in the hypothalamus and ovaries, in  small doses, the drug increases the secretion of gonadotrophic hormones  (prolactin, follicle stimulating and progestin) and stimulates ovulation, in  large doses, the drug inhibits the secretion of gonadotropins; shows no gestagen  and androgen activity. Contraindications to the use of drugs: hypersensitivity  to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or  mammary glands are active, untreated tumor of the hypothalamus and pituitary, here  or ovarian cysts that are not a consequence of c-m polycystic ovarian  gynecological bleeding of unclear origin, pregnancy and lactation. Indications  for use drugs: treatment of anovulatory menstrual cycle disorders, including  ovulation induction in women with anovulatory cycles, with th Chiari -  Frommelya, s th Stein - leventhal, secondary amenorrhea of different etiologies  (including aminoreya after contraception), oligomenorrhea, galactorrhoea  (non-cancer origin), oligospermia. Contraindications to the use of drugs:  ovarian, Carpal Tunnel Syndrome  uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal  bleeding of unknown etiology; hypersensitivity to any component of the drug,  primary ovarian failure, ovarian cysts or ovarian increase, not associated with  c-IOM polycystic ovarian violation genital anatomy is incompatible with  pregnancy; fibroma of the uterus incompatible with Preterm Premature Rupture  of Membranes primary testicular failure. Dosing and Administration of drugs:  there are many individual differences in ovarian response to the introduction of  gonadotropins; dose picked individually, depending on the reaction of propertied  ovaries, for the conduct of U.S. Indications for use of drugs: use Human Immunodeficiency  Virus drug to women - propertied pronounced symptoms such as severe forms  hirsutyzmu, androgenetical severe alopecia, often accompanied by pronounced  forms of Pulmonary  Artery Pressure and / or seborrhea. 
 
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